Superdisintegrants: An effective tool in mouth dissolving tablets

Nearly 35% of general population associated with a number of health-problems like Parkinsonism, mental disability, motion sickness, allergic rhinitis, hypertension and cardiac failure. To overcome such problems, certain innovative drug delivery systems, like Mouth Dissolving Tablets (MDT) have been developed specially for geriatrics and paediatrics patients. Mouth dissolving tablets offers rapid disintegration so as it dissolve very fast in saliva & then easily swallowed without the need of water which is a major benefit over conventional dosage form. The popularity and usefulness of the formulation resulted in development of several mouth dissolving tablet technologies for preparation. In recent past, several manufacturing technologies such as sublimation technique, spray drying technique…etc. are employed to overcome the limitations of conventional tablet dosage forms. Once the mouth dissolving tablets are prepared they are required to be evaluated for various parameters so as to have long term stability and better therapeutic efficacy.