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Analysis of chemical constituents, phytochemical content and in vitro antioxidant activity of trichosanthes dioica plant leaf (less focused valuable medicinal herb) extract

Author: 
Banerjee Swati, Adak Kamala, Adak Mohini Mohan, Ghosh Sumana and Chatterjee Amitava
Subject Area: 
Life Sciences
Abstract: 

The ancient use of Trichosanthes dioica leaves as a valuable remedy in traditional medicine guided the authors to search out for its inherent chemical characteristics responsible for such activity. The present study encompasses a complete analysis of the leaf portion W.R.T. protein, carbohydrate, moisture, vitamin C, minerals, phytochemicals and in-vitro antioxidant activity in term of DPPH and ABTS+ free radical scavenging assay. Experimental data of the leaves were expressed on the basis of a comparative analysis w.r.t. the corresponding Trichosanthes dioica fruits, the data of which were already established. The principal components in general and the carotenoids in particular of the T. dioica leaf may place it at a higher position to act as a nutrient pool to fight against Vitamin deficiency. Although T. dioica leaves are deficient in sodium, potassium and calcium contents in comparison to the fruits, but in term of % of coparison the high iron content (+5924.12%) and lower phytate content (-70%) make the former a very efficient and economic source of iron nutrition to the anaemic. The higher oxalate (+401.57%) and lower calcium (-28.80%) contents of T. dioica leaves make it unsuitable for consumption for the people suffering with Ca-deficiency diseases. Methanolic leaf extract of T. dioica is a better source (in term of % of comparison) of polyphenols (+1068.19%) and flavonoids (+664.84%) than the corresponding contents in the fruit part. Result showed that, the extract exhibited significant DPPH (16% more effective than the fruits) and ABTS+ free radical scavenging activities.

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