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Bacterial Spectrum And Their Antibiogram Among Sputum Samples During Covid-19 pandemic at a tertiary care hospital

Author: 
Dr. Nimmala Sri Harsha, Dr. Srivani, N., Dr. Rajaram, G.
Subject Area: 
Health Sciences
Abstract: 

Introduction: Respiratory tract infections are most frequent of all infections and lower respiratory tract infections are most common worldwide. Immunity plays a significant role in an individual’s defense mechanism against infections. Once immunity specifically innate immunity is affected, people will be more prone for infections especially bacterial infections. Covid-19 pandemic is exhibiting waves of peaks during different months. Bacterial coinfections during viral pandemics are one of the challenges for the health care professionals. Material and Methods: This is a Retrospective study conducted in the department of microbiology S.V. Medical College, Tirupati during January 2021 to June 2021, approved by scientific committee. Total 382 sputum samples were included among which Males were 284 and Females 98. 218 (57%) samples yielded bacterial growth. Laboratory diagnosis was done by routine conventional methods with antibiogram by Kirby Bauer disc diffusion method. Most common organism isolated was Streptococcus pneumoniae followed by Klebsiella, enterobacter, Serratia, S.aureus. ESBL producing Enterobacteriaceae and MRSA were also isolated. Results: In the present study, out of 382 sputum samples, 218(57%) were culture positive and 164(43%) were sterile. Culture positivity was more in the age group of 56-65years. Commonest organism isolated was Streptococcus pneumoniae. Maximum susceptibility shown to cefoperazone –sulbactum, imepenem. Conclusion: As there is increase in prevalence of multi drug resistant organisms were observed, routine culture, antibiogram should be done. Implementation of changes in the local antibiotic policies according to the antibiotic susceptibility testing is needed.

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