An ethnobotanical survey was carried out in the Avidanallavijayapuram (Pappanadu) village of, Orathanadu (tk), Thanjavur (dt), Tamilnadu, India. Interviews and detailed personal discussions were conducted with the herbalist and local people to identify plants and collect the medicinal information for 12 months (from January 2015 to December 2015). The medicinally important plants were botanically identified. Totally 137species of 125 genera belonging to 57 families were reported with ethno medicinal values. Leaves are the mostly used part to prepare medicine. Generally fresh parts are used. The medicinal plants used by villagers were arranged alphabetically followed by botanical name, family name, local name part used, and medicinal uses.