
Study design and Objective: This was a cross sectional retrospective study aimed to identify frequency and classify lymphadenopathy in adult Sudanese patients investigated by fine needle aspiration cytology. Methods: Fine needle aspirates were obtained from 639 patients having enlarged lymph nodes, stained by Pap stain and assessed under a light microscope. Data and findings were analyzed using SPSS program version 16. Results: From the 639 cases, 361 were benign and 278 were malignant with predominance of metastatic cancer. Conclusion: Lymphadenopathy in Sudanese adults can be easily assessed and classified by using fine needle aspiration, as the case in several other populations.