CERTIFICATE

IMPACT FACTOR 2021

Subject Area

  • Life Sciences / Biology
  • Architecture / Building Management
  • Asian Studies
  • Business & Management
  • Chemistry
  • Computer Science
  • Economics & Finance
  • Engineering / Acoustics
  • Environmental Science
  • Agricultural Sciences
  • Pharmaceutical Sciences
  • General Sciences
  • Materials Science
  • Mathematics
  • Medicine
  • Nanotechnology & Nanoscience
  • Nonlinear Science
  • Chaos & Dynamical Systems
  • Physics
  • Social Sciences & Humanities

Why Us? >>

  • Open Access
  • Peer Reviewed
  • Rapid Publication
  • Life time hosting
  • Free promotion service
  • Free indexing service
  • More citations
  • Search engine friendly

How could node-positive breast cancer patients benefit from post-neoadjuvant chemotherapy slnb adopting acosog z1071 end recommendations

Author: 
Ahmed M M Gomaa
Subject Area: 
Health Sciences
Abstract: 

Introduction: axillary lymph node status is one of the most significant prognostic factors that guide treatment strategy in breast cancer. Patients with advanced tumor or axillary nodal metastasis could benefit from neoadjuvant chemotherapy (NAC) resulting in down-staging of the disease. Sentinel lymph node biopsy (SLNB) in patients with axillary nodal disease is debated regarding its identification rate (IR) and false negative rate (FNR). American College of Surgeons Oncology Group (ACOSOG) conducted a large trial to assess SLNB in such patients and it showed depressing outcome resulting in proposition of some recommendations and modification in their methodology when SLNB to be carried out. In this study we adopt ACOSOG Z1071 recommendation to assess SLNB in post-NAC node-positive breast cancer patients. Methods: This study included 42 breast cancer patients with pathologically proved nodal metastasis. SLNB carried out in patients who showed clinical negative nodes after NAC. Three or more SLNs was mandatory to continue the assigned management pathway, while less than 3 nodes or failure to identify any SLN shift the patient to axillary lymph node dissection (ALND). Detailed evaluation of SLNs and nodes yielded from ALND was done and data interpreted to show how far such patient could benefit from such procedure and if any could spared ALND. Results: From 42 patients included in the study clinical conversion rate after NAC to negative axilla was 78.6%. 33 patients underwent SLNB with identification rate of 84.8%. Three or more SLNs were identified in 20 patients. 24% of patients subjected to SLNB were spared axillary dissection. On final evaluation of all retrieved nodes in all limbs of the study we assumed that neoadjuvant chemotherapy resulted in pathological complete response in 35% of our studied group. Conclusions: SLNB following NAC in node-positive patients is feasible and can be a future standard of care with some modification in methodology adopting recommendations released from large concerned trials.

PDF file: 

CALL FOR PAPERS

 

ONLINE PAYPAL PAYMENT

IJMCE RECOMMENDATION

Advantages of IJCR

  • Rapid Publishing
  • Professional publishing practices
  • Indexing in leading database
  • High level of citation
  • High Qualitiy reader base
  • High level author suport

Plagiarism Detection

IJCR is following an instant policy on rejection those received papers with plagiarism rate of more than 20%. So, All of authors and contributors must check their papers before submission to making assurance of following our anti-plagiarism policies.

 

EDITORIAL BOARD

CHUDE NKIRU PATRICIA
Nigeria
Dr. Swamy KRM
India
Dr. Abdul Hannan A.M.S
Saudi Arabia.
Luai Farhan Zghair
Iraq
Hasan Ali Abed Al-Zu’bi
Jordanian
Fredrick OJIJA
Tanzanian
Firuza M. Tursunkhodjaeva
Uzbekistan
Faraz Ahmed Farooqi
Saudi Arabia
Eric Randy Reyes Politud
Philippines
Elsadig Gasoom FadelAlla Elbashir
Sudan
Eapen, Asha Sarah
United State
Dr.Arun Kumar A
India
Dr. Zafar Iqbal
Pakistan
Dr. SHAHERA S.PATEL
India
Dr. Ruchika Khanna
India
Dr. Recep TAS
Turkey
Dr. Rasha Ali Eldeeb
Egypt
Dr. Pralhad Kanhaiyalal Rahangdale
India
DR. PATRICK D. CERNA
Philippines
Dr. Nicolas Padilla- Raygoza
Mexico
Dr. Mustafa Y. G. Younis
Libiya
Dr. Muhammad shoaib Ahmedani
Saudi Arabia
DR. MUHAMMAD ISMAIL MOHMAND
United State
DR. MAHESH SHIVAJI CHAVAN
India
DR. M. ARUNA
India
Dr. Lim Gee Nee
Malaysia
Dr. Jatinder Pal Singh Chawla
India
DR. IRAM BOKHARI
Pakistan
Dr. FARHAT NAZ RAHMAN
Pakistan
Dr. Devendra kumar Gupta
India
Dr. ASHWANI KUMAR DUBEY
India
Dr. Ali Seidi
Iran
Dr. Achmad Choerudin
Indonesia
Dr Ashok Kumar Verma
India
Thi Mong Diep NGUYEN
France
Dr. Muhammad Akram
Pakistan
Dr. Imran Azad
Oman
Dr. Meenakshi Malik
India
Aseel Hadi Hamzah
Iraq
Anam Bhatti
Malaysia
Md. Amir Hossain
Bangladesh
Ahmet İPEKÇİ
Turkey
Mirzadi Gohari
Iran