
Eosinophilic cholecystitis is a rare and poorly understood entity first described in 1949 which diagnosed on the basis of classical presentation of cholecystitis with the trans-mural inflammatory infiltrates predominantly presence of more than 90% eosinophilic with in the gall bladder. It may be idiopathic or it may be associated with other disease conditions, like hyper-eosinophilic syndrome, drug intake, eosinophilic myalgia syndrome, few herbal medicines and some parasitic infestations. We report three cases who presented with pain in right upper quadrant. On ultrasonography of all three cases reveals multiple stones in first & second cases and third case are single stone, which on histopathological was diagnosed as eosinophilic cholecystitis. Retrospective analysis of their histories and their investigations. We present these cases because of their rare occurrence and worst prognosis than cholecystitis.