
The elderly presents a more susceptible profile to the multiplicity of chronic diseases, besides the deterioration of their hepatic and renal functions, compromising the metabolism and the excretion of the medicines. However, this article aims to identify the drug interactions in elderly people using polypharmacy registered in a health. The methodology used in this work aims to describe how the study was conducted, as well as the means used to collect the data. This study is an applied research. "An applied research indicates research of practical interest, where its results are solved”. Once the search for ideas and/or thoughts is perfected, this research is exploratory. The questionnaires were preceded by the informed consent form, and applied by the researchers, in a formal and direct way to the users of the health service. Among the 241 patients analyzed, only 160 answered about the drug therapy administered, the remaining 81 patients did not report when approached. The 160 prescriptions showed a total of 357 potency drug interactions, with an average of 2.23 interactions per patient. Another study performed in intensive care unit patients reported a mean of 2.3 interactions per patient, corroborating with the results found, since drug interaction is one of the main variables that affect the therapeutic result and the higher the number of medications administered , consequently the greater the possibility of its occurrence. However, the pharmacist plays a fundamental role in pharmacotherapy, accompanying patients with polytherapy, analyzing each case in order to identify possible health risks by undue administrations and associations of medications, and thus intervene in pharmacotherapy when necessary.