
The contamination of metals is a major environmental problem and, especially in the aquatic environment. This study aims to identify and determine the levels the heavy metals (HMs) in the tilapia fish tissue in two localities in the Northern State, Sudan. The tilapia fish tissue was analyzed in the Central Petroleum Laboratories, Khartoum, Sudan, using Inductively Coupled Plasma– Optical Emission Spectrometer ICP-OES 725 E) instrument to determine Zn, Pb, Cu, Co, Ni, Cd, Mo, Cr, Fe, Li, and Hg levels and compare their concentrations with the permissible levels (PLs), using the Complete Randomized Design (CRD) with three replications. The results from two localities reflects the presence of high amounts of HMs, the two types of tissue (muscular & liver) from Tilapia fish demonstrated the presence of high quantities of Lead and Nickel in muscle tissue more than the permissible limits (0.214 and 0.5 -0.6 ppm) according to FAO/WHO1999 EPA2003. Similar in the Liver tissue also demonstrated high quantities of Lead more than the permissible limits according to FAO/WHO (1999) EPA (2003). It is concluded that the accumulation of Heavy metals in the aquatic environment in the northern state requires more attention from the authorities.